state what would happen to the ion pumping activity and atp hydrolyzing activity of the na /k pump if the plasma membrane of animal cells was made entirely permeable to na . what would happen to the na distribution?

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15-12-2022
Biology

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state what would happen to the ion pumping activity and atp hydrolyzing activity of the na /k pump if the plasma membrane of animal cells was made entirely permeable to na . what would happen to the na distribution?

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contexto1220 contexto1220 · Answer 1 · 2022-12-21T09:03:00+01:00

The distribution of Na will cause the cells to ne hypertonic and thus Failure of the Na⁺-K⁺ pump can cause cells to swell.

The osmotic pressure of a cell is the sum of the concentrations of various ionic species and many proteins and other organic compounds inside the cell. If this is higher than the osmotic pressure outside the cell, water will flow into the cell by osmosis. Thus, inhibition of this pump causes cell depolarization.

This is due not only to changes in the Na+ and K+ concentration gradients, but also to the loss of the potential component of the resting membrane potential. Partial inhibition of the electrogenic Na+/K+ pump results in cell swelling and an increase in the number of functional Na+/K+ ATPase molecules within the membrane. This compensates for the effects caused by pump suppression.