Key organs for development and metabolism get instructions from the brain via the neurological system via chemical messengers conveyed by the endocrine system throughout the homeostasis by the body.
Negative feedback physiological control that maintain homeostasis control the endocrine system. This regulates the hormone levels and how other bodily systems are affected by it. For instance, the hormones generated by the pancreas, insulin and glucagon, regulate blood sugar levels. A number of control systems that endocrine system operate at the organ, tissue, or cellular level work together to maintain homeostasis. Among these control mechanisms endocrine system is the provision of substrates.
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