optimizing the conditions and use of synthetic matrix for three-dimensional in vitro retinal differentiation from mouse pluripotent cells. tissue eng part c methods

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14-10-2022
Biology

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optimizing the conditions and use of synthetic matrix for three-dimensional in vitro retinal differentiation from mouse pluripotent cells. tissue eng part c methods

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rathipushpendra345 rathipushpendra345 · Answer 1 · 2022-10-18T07:44:51+02:00

Recent research has shown that a three-dimensional approach to retinal differentiation tissue development from pluripotent cells is a reliable method.

Improves repeatability and efficiency of retinal differentiation in organoid cultures by combining the best conditions and methods for three-dimensional retinal differentiation from mouse embryonic cells. Retinal induction can be accomplished without the need of Matrigel by using a synthesised oligopeptide, which is a step closer to xeno-free settings for cell generation. With defined medium conditions, retinal tissue and cell production can be scaled up greatly for use in drug discovery, disease modelling, and transplantation. These conditions also significantly reduce variability within and between batches.

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