Major characteristics of Drug theory is
Drug plus Receptor = D--R = Response
What is Drug theory?
The idea is that different medications bind with different places (receptors), and that this connection results in a conformational change that leads to a signal.
Agonist and antagonist activities are mediated via receptors.
-Requires knowledge of potency and efficacy (max effect).
Agonists attach to receptors and serve as endogenous ligands. Antibodies may or may not bind receptors; they don't elicit a typical reaction and obstruct biological action.
-requires the agonist to function (function is dependent on the agonist's "normal tone").
-Receptors are also in charge of the drug's ability to function selectively.
increasing the benefit-to-risk ratio; requiring specificity and the right fit in order to elicit a response.
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