The chemical receptors are the main influence on the regions of the brain responsible for maintaining respiratory homeostasis is carbon dioxide.
How does carbon dioxide increases?
The main chemoreceptors involved in respiratory feedback are: Central chemoreceptors: These are located on the ventrolateral surface of medulla oblongata and detect changes in the pH of spinal fluid. They can be desensitized over time from chronic hypoxia (oxygen deficiency) and increased carbon dioxide.
Thus, option "B" is correct.
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