Answer: In all, between 1492 and 1650, perhaps 90 percent of the first Americans had died. This loss is considered among the largest demographic disasters in human history. By stripping the Americas of much of the human population, the Columbian Exchange rocked the region's ecological and economic balance. The Atlantic slave trade was the transfer of Africans from primarily West Africa to parts of the Americas between the 16th and 19th century, a large part of the Columbian Exchange. About 10 million Africans arrived in the Americas on European boats as slaves.
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