Respuesta :
Answer:
Question 1: "Should siblings of a healthy child who is younger
than age 6 months be vaccinated?"
The author opined that because of the vulnerability of the infants, every family should endeavour to vaccinate them annually for protection against serious infections.
See quote from the text :
"Yes, it is especially important that all household contacts
of children too young to be vaccinated against
influenza (i.e., younger than age 6 months) receive
annual influenza vaccination to protect the infant from
serious infection. This is very important because of these
infants are too young to be vaccinated and are most
vulnerable to complications from influenza."
Question 2: Why are different influenza vaccines (Fluzone High-
Dose; Fluad) available for adults 65 and older?
The author was of the view that age affect the older people's responses to develop strong immunity against influenza vaccine. This was what led to the manufacturers of the vaccine for example, Fluzone High-Dose, to contain a larger amount of antigens to give them a better immune response and provides better protection against influenza."
View Quotes from the text
"Ageing decreases the body’s ability to develop a good
immune response after getting influenza vaccine. Vaccine
manufacturers have taken two different
approaches to improve the immune response in older
people. For Fluzone High-Dose, a larger amount of
antigen in the vaccine gives older people a better
immune response and provides better protection
against influenza."
Explanation:
"Should siblings of a healthy child who is younger
than age 6 months be vaccinated?"
Yes, it is especially important that all household contacts
of children too young to be vaccinated against
influenza (i.e., younger than age 6 months) receive
annual influenza vaccination to protect the infant from
serious infection. This is very important because of these
infants are too young to be vaccinated and are most
vulnerable to complications from influenza.
Why are different influenza vaccines (Fluzone High-
Dose; Fluad) available for adults 65 and older?
Ageing decreases the body’s ability to develop a good
immune response after getting influenza vaccine. Vaccine
manufacturers have taken two different
approaches to improve the immune response in older
people. For Fluzone High-Dose, a larger amount of
antigen in the vaccine gives older people a better
immune response and provides better protection
against influenza.
Data from clinical trials comparing
regular Fluzone to Fluzone High-Dose among people
age 65 and older indicate that higher antibody levels
occur after vaccination with Fluzone High-Dose. Compared
to standard Fluzone, the high-dose formulation
reduced laboratory-confirmed influenza by about 24%.
For Fluad, the manufacturer includes an adjuvant to
improve the response to the vaccine. The adjuvant is
called MF59 and is an oil-in-water emulsion containing
squalene, an oil that occurs naturally in many plants
and animals. Fluad is the first influenza vaccine
licensed in the U.S. that contains an adjuvant. Compared
to trivalent influenza vaccine, one study found
that Fluad reduced laboratory-confirmed influenza by
about 63%.
Both Fluzone High-Dose and Fluad are trivalent formulations
(containing H3N2, H1N1 and B viruses) and
both are approved for use only in people 65 years of age
and older. Neither vaccine should be given to people
younger than 65 years.
CDC has stated no preference for using high-dose or
adjuvanted vaccine or standard-dose or recombinant
influenza vaccine for people age 65 and older. But it is
reasonable for a person age 65 years or older to receive
either Fluzone High-Dose or Fluad if it is readily available.
However, influenza vaccination should not be
deferred if the high-dose or adjuvanted formulation is
not immediately available. Standard dose or recombinant
vaccine should be given.
Note: Find attached document of
"Influenza:
Questions and Answers
Information about the disease and vaccines
