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__________________________ is often caused by CAD, and it happens when one or more parts of the heart muscle does not get enough blood because of the blockage (caused by CAD). When that happens, the heart is damaged so severely that part of the heart (a muscle) dies.

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Answer:

The correct answer to fill the blank will be "Atherosclerosis"

Explanation:

CAD is the acronym for Coronary Artery Disease. The Atherosclerosis can be defined as the formation of cholesterol or plaque  inside the arteries that supply blood to the heart. When this happens is possible that the affected side of the heart doesn't receive enough blood, oxygen or nutrients and this affected part of the muscle can die.