Insulin is a protein that is produced by pancreatic cells and secreted into bloodstream. which of the following options correctly lists the order of the structures through which insulin passes from its production to its exit from the cell?
A. Rough ER, transport vesicles, Golgi Apparatus transport vesicles, cell membrane
B. Rough ER, lysosomes, tranport vesicles, cell membrane
C. Rough ER, Golgi Apparatus smooth ER, cell membrane

Respuesta :

Answer:

A. Rough ER, transport vesicles, Golgi Apparatus transport vesicles, cell membrane

The CORRECT order of the structures through which insulin passes from its production to its exit from the cell is Rough ER >> transport vesicles >> Golgi Apparatus >> transport vesicles >> cell membrane (Option A).

  • Insulin is a peptide hormone synthesized in the beta cells of the pancreas.

  • This hormone (insulin) is processed in the endomembrane system.

  • The removal of the signal peptide during insertion into the rough endoplasmic reticulum (RER) generates proinsulin.

  • Subsequently, proinsulin is exposed to peptidases that produce insulin within the RER.

  • This protein (insulin) is then transported from the rough endoplasmic reticulum (RER) in transport vesicles to the Golgi apparatus.

  • Within the Golgi apparatus, insulin is processed into mature insulin and packaged into secretory vesicles which are transported to the cell membrane via transport vesicles.

In conclusion, the CORRECT order of the structures through which insulin passes from its production to its exit from the cell is Rough ER >> transport vesicles >> Golgi Apparatus >> transport vesicles >> cell membrane (Option A).

Learn more in:

https://brainly.com/question/8010049?referrer=searchResults