JY is a 58 year old male who was hospitalized for a total knee replacement. He was given unfractionated heparin and developed heparin-induced thrombocytopenia (HIT). Argatroban was ordered at a dose of 2 mcg/kg/min. The pharmacy mixes a concentration of 100 mg argatroban in 250 mL of DSW. JY weighs 85 kg. How many mL/hour should the nurse infuse to provide the dose? Round to the nearest whole number. .

Respuesta :

Answer:

The nurse infuse [tex]26ml/hr[/tex] to provide the dose.

Step-by-step explanation:

Argatroban was ordered at a dose of 2 mcg/kg/min.

JY weighs 85 kg.

So, Argatroban was ordered= [tex]2 \times 85[/tex]

                                              = [tex]170mcg/min.[/tex]

Convert the dose in mg/hr

1 hr = 60 minutes and 1 mg = 1000 mcg

So, Dose in ml/hr = [tex]170 \times \frac{60}{1000}[/tex]

                             = [tex]10.2 mg/hr[/tex]

Now to find in 250 mL of DSW. JY weighs 85 kg. How many mL/hour should the nurse infuse to provide the dose?

The nurse infuse to provide the dose = [tex]\text{Dose ordered} \times \frac{\text{volume available}}{\text{Dose available}}[/tex]

The nurse infuse to provide the dose = [tex]10.2 mg/hr \times \frac{250 ml}{100 mg}[/tex]

The nurse infuse to provide the dose = [tex]26ml/hr[/tex]

Hence The nurse infuse [tex]26ml/hr[/tex] to provide the dose.