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14-09-2019
Biology

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Which end of a new mRNA transcript gets a cap during processing in the nucleus?
a. the top
b. the bottom
c. the 3' end
d. the 5' end

Respuesta :

namordu namordu

17-09-2019

Answer:

d. the 5' end

Explanation:

Capping is a co-transcriptional modification made to RNA in the nucleus after the first 25–30 nts are incorporated into the nascent transcript, which is synthetized in the 5' ---> 3' direction.

The cap consists of a methylated guanosine nucleotide added to the 5' end of the new mRNA transcript, and is important for several processes, which include:

Protection of the mRNA from the attack of phosphatases and nucleases.
Splicing of mRNA in the nucleus.
Nuclear export of the mRNA to the cytoplasm.
Cap-dependent protein synthesis.

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