Fructose 2,6-bisphosphate is a regulator of the following reaction. Please explain how it responds to glucagon and insulin stimulation and regulates glycolysis and gluconeogenesis pathways.
a) Define Fructose 2,6-bisphosphate and its role as a regulator in metabolic pathways.
b) Describe the mechanisms by which Fructose 2,6-bisphosphate responds to glucagon and insulin stimulation.
c) Explain how Fructose 2,6-bisphosphate regulates glycolysis and gluconeogenesis pathways in response to hormonal signals.
d) Discuss the importance of Fructose 2,6-bisphosphate in maintaining metabolic homeostasis and its potential as a therapeutic target.