Carbamazepine(CBZ)
Treats?
•Tegretol level range=remember auto-induction of its own metabolism may start 3-5 days after initiation = therefore decreases plasma levels( a known phenomenon observed when a drug induces the enzymes responsible for its own metabolism)
•Can produce Ataxia even at therapeutic doses
Like valproate it acts primarily by inhibiting sodium channels and augmenting GABA transmission.
Not a popular drug for treating bipolar disorder because of many side effects, SJS, agranulocytosis, constant adjustment of dose.
•Tegretol level range=remember auto-induction of its own metabolism may start 3-5 days after initiation = therefore decreases plasma levels
•Can produce Ataxia even at therapeutic doses
a) Epilepsy, Bipolar disorder
b) Anxiety disorder, Panic disorder
c) Depression, Schizophrenia
d) Obsessive-compulsive disorder, Major depressive disorder