CafeÌ-au-lait spots look like tan-to-light brown stains that have irregular borders. They can be located anywhere on the body. Which of the following is a correct statement?
1) They are associated with neurofibromatosis or von Recklinghausen's disease
2) They may be considered as precancerous after a biopsy
3) They are more common in darker-skinned children
4) They are associated with Wilson's disease