If you were to replace the DNA-binding domain of the Yeast Gal4 protein with the DNA binding domain from the Lac repressor, this protein would no longer regulate the transcription of GAL genes in yeast.
A: Draw two different modular diagrams (just pairs of labeled rectangles of domains) of the different functional domains you would expect to find in the Gal4 protein and in the engineered protein.
B: Why does the engineered protein no longer regulate transcription of the GAL genes? How might you alter the DNA-binding site recognized by the new chimeric protein to rescue it to make it functional in activating transcription of GAL genes?