A 58-year-old man is admitted to the hospital with jaundice and nosebleeds.
CBC and WBC differential counts:
WBC: 9.5 Band neutrophils: 15
RBC: 3.10 Segmented neutrophils: 50
Hgb: 10.4 Lymphocytes: 25
Hct: 32.0 Monocytes: 8
MCV: 103.1 Eosinophils:
MCH: 33.5 Basophils:
MCHC: 32.5 Metamyelocytes: 2
RDW: 12.9 Myelocytes:
PLT: 119.9 Promyelocytes:
PT: 16 sec
aPTT: 53 sec
Direct bilirubin: increased
ALT: elevated
AST: elevated
ALP: elevated
Interpret the coagulation screening test.
Based on all the data provided, what condition is most likely?
What information is most diagnostic?
What physiologic abnormality most likely underlies the nosebleeds?